MAKATUSSIN SYROP SECRETS

desvenlafaxine will raise the amount or effect of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Caution/Watch. Desvenlafaxine inhibits CYP2D6; with larger desvenlafaxine doses (ie, 400 mg) minimize the CYP2D6 substrate dose by approximately 50%; no dosage adjustment necessary with desvenlafaxine doses seven consecutive days straight aw